RAND Forecasting Initiative

What will the total amount of seed funding for biotech startups in the U.S. be in 2025 and 2026 combined, according to Labiotech?

Question Ends:
Jan 01, 2027 05:00AM UTC
(1 year from now)

Forecast Last Updated:
Nov 27, 2025 03:27PM UTC
(21 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Less than $350 million	43%	42%	+1%	+1%
More than or equal to $350 million but less than $450 million	33%	36%	-3%	+2%
More than or equal to $450 million but less than $550 million	17%	16%	+1%	-2%
More than or equal to $550 million but less than $650 million	5%	5%	+0%	-1%
More than or equal to $650 million	2%	1%	+1%	+0%

What will the total amount of seed funding for biotech startups globally be in 2025 and 2026 combined, according to Labiotech?

Forecast Count:
4 Forecasts

Question Ends:
Jan 01, 2027 05:00AM UTC
(1 year from now)

Forecast Last Updated:
Nov 27, 2025 03:58PM UTC
(21 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Less than $1 billion	80%	87%	-7%	+9%
More than or equal to $1 billion but less than $1.2 billion	15%	9%	+6%	-6%
More than or equal to $1.2 billion but less than $1.4 billion	4%	2%	+2%	-2%
More than or equal to $1.4 billion but less than $1.6 billion	1%	1%	+0%	-1%
More than or equal to $1.6 billion	0%	0%	+0%	+0%

Will scientists successfully create a synthetic cell from chemically synthesized components by 1 January 2035?

Forecast Count:
5 Forecasts

Question Ends:
Jul 01, 2026 04:00AM UTC
(6 months from now)

Forecast Last Updated:
Nov 28, 2025 10:41AM UTC
(21 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Yes	5%	10%	-5%	+0%
No	95%	90%	+5%	+0%

Will government agencies in the U.S., EU, or UK classify mirror biology research under dual-use oversight mechanisms by 31 December 2030?

Forecast Count:
5 Forecasts

Question Ends:
Jul 01, 2026 04:00AM UTC
(6 months from now)

Forecast Last Updated:
Nov 28, 2025 11:23AM UTC
(21 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Yes	35%	45%	-10%	-2%
No	65%	55%	+10%	+2%

Will mirror reagents or products be added to the Australia Group export control list or national controlled biological agent lists in the U.S., UK, or Canada by 31 December 2032?

Forecast Count:
5 Forecasts

Question Ends:
Jul 01, 2026 04:00AM UTC
(6 months from now)

Forecast Last Updated:
Nov 28, 2025 11:25AM UTC
(21 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Yes	22%	28%	-6%	+0%
No	78%	72%	+6%	+0%

Will scientists be able to assemble a ribosome in vitro, composed entirely of synthetic proteins and RNA, without the use of cell-derived materials by 2030?

Forecast Count:
4 Forecasts

Question Ends:
Jul 01, 2026 04:00AM UTC
(6 months from now)

Forecast Last Updated:
Nov 28, 2025 11:40AM UTC
(20 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Yes	68%	38%	+30%	+2%
No	32%	62%	-30%	-2%

Will a U.S. or non-U.S. entity train an artificial intelligence model at least 10^27 computational operations (FLOPs) before 1 June 2027?

Forecast Count:
4 Forecasts

Question Ends:
Jun 01, 2027 04:00AM UTC
(1 year from now)

Forecast Last Updated:
Nov 28, 2025 01:06PM UTC
(20 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
U.S. Entity	90%	82%	+8%	+3%
Non-U.S. Entity	45%	57%	-12%	+1%

Will the FDA have authorized a medical device that incorporates LLM-based functionality by 31 March 2026?

Forecast Count:
1 Forecast

Question Ends:
Apr 01, 2026 04:00AM UTC
(3 months from now)

Forecast Last Updated:
Nov 28, 2025 02:09PM UTC
(20 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Yes	5%	5%	+0%	+3%
No	95%	95%	+0%	-3%

In the next 18 months, will a Russian government cyber attack occur against energy or transportation infrastructure within a NATO country that produces a kinetic effect, causing physical damage or human casualties?

Forecast Count:
14 Forecasts

Question Ends:
Jan 01, 2026 05:00AM UTC
(13 days from now)

Forecast Last Updated:
Dec 15, 2025 12:38PM UTC
(3 days ago)

Answer	Your Forecast	Forecast Window	Forecast Expiration	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Yes	4%	Dec 15, 2025 to Jun 15, 2027	Mar 15, 2026	6%	-2%	+0%
No	96%	Dec 15, 2025 to Jun 15, 2027	Mar 15, 2026	94%	+2%	+0%

Will the U.S. federal government enact legislation that substantively regulates or authorizes regulation of artificial intelligence systems or their development before 1 January 2026?

Forecast Count:
9 Forecasts

Question Ends:
Jan 01, 2026 05:00AM UTC
(13 days from now)

Forecast Last Updated:
Dec 15, 2025 01:03PM UTC
(3 days ago)

Answer	Your Forecast	Current Consensus	Difference from Consensus	Change in Consensus Since Last Forecast
Yes	0%	1%	-1%	0%
No	100%	99%	+1%	0%

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